Work

Supplementary Figures S1 - S7 from Real-Time Imaging Reveals Local, Transient Vascular Permeability, and Tumor Cell Intravasation Stimulated by TIE2hi Macrophage–Derived VEGFA

Year: 2023

Type: supplementary-materials

Abstract: Supplementary Figure S1. TMEM formation with tumor stage in PyMT. Supplementary Figures S2. Tumor cell intravasation occurs at TMEM along with local, transient blood vessel permeability. Supplementary Figure S3. Tumor cell intravasation occurs at TMEM with local, transient blood vessel permeability in a human patient-derived xenograft model of triple negative breast cancer. Supplementary Figure S4. The sliding window measurement. Supplementary Figure S5. 155 kDa dextran-TMR does not extravasate. Supplementary Figure S6. VEGFAHi TEMs are enriched at TMEM and sites of pericyte depletion. Supplementary Figure S6. Vascular VE-Cadherin is decreased in the presence of Tie2Hi/VEGFAHi macrophages in TMEM in human breast cancer.

DOI: 10.1158/2159-8290.22531334.v1

Authors: Allison S. Harney, Esther N. Arwert, David Entenberg, Yarong Wang, Peng Guo, Bin-Zhi Qian, Maja H. Oktay, Jeffrey W. Pollard, Joan G. Jones, John S. Condeelis

Language: English

Topic: Angiogenesis and VEGF in Cancer

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4362538662

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