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Supplementary Figures S1 - S3 from Real-Time Intravital Imaging Establishes Tumor-Associated Macrophages as the Extraskeletal Target of Bisphosphonate Action in Cancer

Year: 2023
Type: supplementary-materials
Abstract: Supplementary Figure S1. Fluorescently-labelled bisphosphonate is present in the macrophage-rich region of 4T1 mammary tumours in vivo. Supplementary Figure S2. N-BP colocalises with microcalcifications, detected by calcein labelling in 4T1 mammary tumours. Supplementary Figure S3. TAMs do not take up N-BP as efficiently in the B16.F10 melanoma model compared to the 4T1 mammary tumour model.
DOI: 10.1158/2159-8290.22530390.v1
Authors: Simon Junankar, Gemma Shay, Julie Jurczyluk, Naveid Ali, Jenny Down, Nicholas Pocock, Andrew Parker, Akira Nguyen, Shuting Sun, Boris Kashemirov, Charles E. McKenna, Peter I. Croucher, Alexander Swarbrick, Katherine Weilbaecher, Tri Giang Phan, Michael J. Rogers
Language: English
Subfield: Oncology
Field: Medicine
Open Access status: gold
OpenAlex ID: W4362538790
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