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Supplementary Fig. S2 from Salmonella-Based Therapy Targeting Indoleamine 2,3-Dioxygenase Coupled with Enzymatic Depletion of Tumor Hyaluronan Induces Complete Regression of Aggressive Pancreatic Tumors

Year: 2023

Type: supplementary-materials

Abstract: Treatment dose and scheduling. (A) Doses and schedule of therapies administered to tumor bearing mice. (B) Control groups treated with gemcitabine alone and NAB alone. Mice were implanted with 5x105 KPC-luc cells on day 0 and treated as specified in (A). Images are representative mice for multiple experiments using identical treatment regimens.

DOI: 10.1158/2326-6066.22537505.v1

Authors: Edwin R. Manuel, Jeremy Chen, Massimo D'Apuzzo, Melanie G. Lampa, Teodora I. Kaltcheva, Curtis B. Thompson, Thomas Ludwig, Vincent Chung, Don J. Diamond

Language: English

Topic: Cancer Research and Treatments

Subfield: Biotechnology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4362539860

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