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Supplement Figure 3 from Targeting Mitochondrial Proline Dehydrogenase with a Suicide Inhibitor to Exploit Synthetic Lethal Interactions with p53 Upregulation and Glutaminase Inhibition

Year: 2023
Type: other
Abstract: Supplement Figure 3. Confocal images of control and N-PPG treated ZR-75-1 cell cultures show absence of mitochondrial membrane recruitment of PINK/PARKIN complex (A), despite positive induction of mitochondrial GRP-75 import (B), within 24 h of N-PPG treatment.
DOI: 10.1158/1535-7163.22506033.v1
Authors: Gary K. Scott, Christina Yau, Beatrice C. Becker, Sana Khateeb, Sophia Mahoney, Martin Borch Jensen, Byron Hann, Bryan J. Cowen, Scott D. Pegan, Christopher C. Benz
Language: English
Subfield: Cancer Research
Open Access status: gold
OpenAlex ID: W4362542860
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