Work

Figure S1-S4 and Table S1-S2 from KDM5B Promotes Drug Resistance by Regulating Melanoma-Propagating Cell Subpopulations

Year: 2023

Type: other

Abstract: Figure S1. Responses of different YUMM cell lines to BRAFi treatment; Figure S2. Inhibition of KDM5 family members by shRNA knockdown and pan-KDM5 inhibitors; Figure S3. Subpopulation composition in tumors of different volumes; Figure S4. In vivo BRAFi/MEKi treatment of grafted YUMM1.7 tumors induced Kdm5b expression and increased CD34- subpopulation; Table S1. List of RT-qPCR primers; Table S2. Subpopulation composition of different YUMM cell lines.

DOI: 10.1158/1535-7163.22506975

Authors: Xiaoni Liu, Shang-Min Zhang, Meaghan K. McGeary, Irina Krykbaeva, Ling Lai, Daniel J. Jansen, Stephen C. Kales, Anton Simeonov, Matthew D. Hall, Daniel P. Kelly, Marcus W. Bosenberg, Qin Yan

Institutions: Yale University, University of Pennsylvania, National Institutes of Health, National Center for Advancing Translational Sciences

Language: English

Topic: Melanoma and MAPK Pathways

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4362548014

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