Work

Fig S4 from World Trade Center Dust Exposure Promotes Cancer in PTEN-deficient Mouse Prostates

Year: 2023

Type: other

Abstract: Fig. S4. Effect of direct introduction of WTC dust to the mouse prostate. A, Approach injecting solubilized WTC dust (2x 1 μl injections per prostate) and evaluation 6-8 weeks later. B, Histological low magnification image showing prostate enlargement after dust injection. C, Gross images showing a PBS control injected prostate (panel 1) and prostates with WTC dust injection (panels 2, 3, 4). D, Histological high magnification view showing immune cell infiltration in WTC dust injected prostate. E, Gene expression profiles for two independent prostates injected with WTC dust normalized to PBS control prostates (bars: B, C1, C3 = 2000 μM, C2, C4 = 5000 μM, D = 250 μM).

DOI: 10.1158/2767-9764.22544751.v1

Authors: Lin Wang, Yitian Xu, Licheng Zhang, Kyeongah Kang, Andriy Kobryn, Kensey Portman, Ronald E Gordon, Ping-Ying Pan, Emanuela Taioli, Stuart A Aaronson, Shu-Hsia Chen, David J Mulholland

Language: English

Topic: Prostate Cancer Treatment and Research

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4362549552

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