Supplementary Figure 4 from Targeted DNA Methylation Screen in the Mouse Mammary Genome Reveals a Parity-Induced Hypermethylation of Igf1r That Persists Long after Parturition
Year: 2023
Type: supplementary-materials
Abstract: Supplemental Figure S4. Full representation of CpG methylation analysis in the confirmation of Methyl-Seq DNA methylation by bisulfite sequencing. (A) The percent methylation for each CpG site after bisulfite sequencing on mammary gland genomic DNA is represented. Each of the top differentially methylated genes chosen for validation are depicted. (B) Bisulfite sequencing data of all clones from each animal are shown. Each circle represents a CpG site and each horizontal line represents DNA from a separate clone. Open circles = unmethylated, and closed circles = methylated.
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: gold
OpenAlex ID: W4362550388