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Supplementary Figure 1 from Elucidating Distinct Roles for NF1 in Melanomagenesis

Year: 2023

Type: supplementary-materials

Abstract: PDF file - 96K, Schwann cells (RT4) expressing an inducible RAF construct (∆RAF:ER) were treated with the indicated concentrations of hydroxy-tamoxifen (4-OHT) in the absence and presence of a short hairpin RNA (shRNA) specific for NF1. RAS-GTP levels were assessed using a RAS pulldown assay. Immunoblots on total cell lysates are shown.

DOI: 10.1158/2159-8290.22529841

Authors: Ophélia Maertens, Bryan Johnson, Pablo Hollstein, Dennie T. Frederick, Zachary A. Cooper, Ludwine Messiaen, Roderick T. Bronson, Martin McMahon, Scott Granter, Keith Flaherty, Jennifer A. Wargo, Richard Marais, Karen Cichowski

Language: English

Topic: Neurofibromatosis and Schwannoma Cases

Subfield: Neurology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4362550684

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