Supplementary Figures S1-S16 from NVL-520 Is a Selective, TRK-Sparing, and Brain-Penetrant Inhibitor of ROS1 Fusions and Secondary Resistance Mutations
Year: 2023
Type: supplementary-materials
Abstract: NVL-520 Modeling, Properties, Biochemical Activity, Cellular Activity, and In Vivo Activity
Authors: Alexander Drilon, Joshua C. Horan, Anupong Tangpeerachaikul, Benjamin Besse, Sai-Hong Ignatius Ou, Shirish M. Gadgeel, D. Ross Camidge, Anthonie J. van der Wekken, Linh Nguyen-Phuong, Adam Acker, Clare Keddy, Katelyn S. Nicholson, Satoshi Yoda, Scot Mente, Yuting Sun, John R. Soglia, Nancy E. Kohl, James R. Porter, Matthew D. Shair, Viola Zhu, Monika A. Davare, Aaron N. Hata, Henry E. Pelish, Jessica J. Lin
Institutions: Memorial Sloan Kettering Cancer Center, Nuvalent, Inc. (United States), Institut Gustave Roussy, University of California, Irvine Medical Center, Henry Ford Health, Henry Ford Hospital, University of Colorado Cancer Center, University Medical Center Groningen, University of Groningen, Massachusetts General Hospital, Oregon Health & Science University, Harvard University
Language: English
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: gold
OpenAlex ID: W4362551763