Supplemental Methods and Figures 1 - 11 from Three Steps to Breaking Immune Tolerance to Lymphoma: A Microparticle Approach
Year: 2023
Type: supplementary-materials
Abstract: Figure S1. Synthesis and characterization of Dox MPs. Figure S2. Dox MPs enhance phagocytosis of A20 by DCs. Figure S3. Dox MPs exert similar effects to soluble Dox in human cell lines. Figure S4. All therapy components are required for maximum efficacy. Figure S5. Ab dose used is optimal. Figure S6. Three-step therapy and Ab therapy induce comparable tumor necrosis. Figure S7. Three-step therapy induces comparable Treg, cDC and MDSC infiltration into tumors. Figure S8. No differences in T cells were seen in draining lymph nodes. Figure S9. No differences in T cell activation phenotype were seen in draining lymph nodes. Figure S10. No differences in antigen-specific responses were seen in lymphoid tissues. Figure S11. Three-step therapy is efficient at reducing EL4 tumor burdens.
Language: English
Subfield: Immunology
Field: Immunology and Microbiology
Domain: Life Sciences
Open Access status: gold
OpenAlex ID: W4362551812