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Supplementary Fig. S8 from Salmonella-Based Therapy Targeting Indoleamine 2,3-Dioxygenase Coupled with Enzymatic Depletion of Tumor Hyaluronan Induces Complete Regression of Aggressive Pancreatic Tumors

Year: 2023
Type: supplementary-materials
Abstract: Detection of PMN in extracted tumors of PEGPH20/shIDO-ST treated mice. Mice treated with PEGPH20/shScr-ST or PEGPH20/shIDO-ST were euthanized and tumors extracted 96 hours post-ST treatment. One hour prior to euthanization, mice were injected with NS-NIR reagent. Tumors were imaged using a Xenogen 100 equipped with an ICG filter set.
DOI: 10.1158/2326-6066.22537481
Authors: Edwin R. Manuel, Jeremy Chen, Massimo D'Apuzzo, Melanie G. Lampa, Teodora I. Kaltcheva, Curtis B. Thompson, Thomas Ludwig, Vincent Chung, Don J. Diamond
Language: English
Subfield: Biotechnology
Open Access status: gold
OpenAlex ID: W4362551937
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