Supplementary Fig. S1 from Salmonella-Based Therapy Targeting Indoleamine 2,3-Dioxygenase Coupled with Enzymatic Depletion of Tumor Hyaluronan Induces Complete Regression of Aggressive Pancreatic Tumors
Year: 2023
Type: supplementary-materials
Abstract: Generation of KPC-luc orthotopic model. (A) 28 day orthotopic KPC tumor (top, 2050 mm3) extracted from untreated C57BL/6 mouse versus normal C57BL/6 pancreas (bottom, 84 mm3). (B) KPC-luc cell line incubated with increasing titration of D-luciferin and imaged using a Xenogen 100 IVIS (C) 5x105 KPC-luc cells were implanted into the pancreas of C57BL/6 mice and growth monitored for 21 days. Representative mouse shown. (D) Kaplan-Meier curve for mice (n=10) implanted with 5x105 KPC-luc cells.
Language: English
Subfield: Biotechnology
Domain: Life Sciences
Open Access status: gold
OpenAlex ID: W4362552161