Supplementary Figure 1.Optimization IHC on pilot series of cHL cases. from Classical Hodgkin Lymphoma with Reduced β2M/MHC Class I Expression Is Associated with Inferior Outcome Independent of 9p24.1 Status
Year: 2023
Type: supplementary-materials
Abstract: Three distinct patterns of staining of HRS cell membranes were observed relative to the staining of reactive inflammatory cells: "positive" (Pos), "decreased" (Dec) and "negative" (Neg) for β2M, MHC class I and MHC class II. CHL #1: β2M and MHC class I positive, MHC class II negative; cHL #2: beta2M and MHC class I decreased, MHC class II positive; cHL #3: beta2M and MHC class I negative, MHC class II decreased. Black arrows highlight individual HRS cells or two adjacent HRS cells with distinct patterns of membrane staining, as indicated.
Authors: Margaretha G.M. Roemer, Ranjana H. Advani, Robert A. Redd, Geraldine S. Pinkus, Yasodha Natkunam, Azra H. Ligon, Courtney F. Connelly, Christine J. Pak, Christopher D. Carey, Sarah E. Daadi, Bjoern Chapuy, Daphne de Jong, Richard T. Hoppe, Donna S. Neuberg, Margaret A. Shipp, Scott J. Rodig
Language: English
Subfield: Pathology and Forensic Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: gold
OpenAlex ID: W4362567250