Supplementary Figures 1 - 5, Tables 1, 5 - 9 from Breast Cancer Neoantigens Can Induce CD8+ T-Cell Responses and Antitumor Immunity
Year: 2023
Type: supplementary-materials
Abstract: Supplementary Figure 1. H&E of WHIM30, WHIM35 and WHIM37 parental tumors. Supplementary Figure 2. Peptides corresponding to prioritized neoantigens can induce strong surface expression of HLA class I molecules. Supplementary Figure 3. Indirect tumor-specific immune response. Supplementary Figure 4. The immune response to neoantigens is HLA-specific. Supplementary Figure 5. Prioritized neoantigens induce immune responses in HLA-A0201 transgenic. Supplementary Table 1. Patient clinical characteristics. Supplementary Table 5. Summary of candidate neoantigens identified by exome sequencing. Supplementary Table 6. HLA typing. Supplementary Table 7. Candidate neoantigens and HLA class I predicted binding affinities for WHIM30. Supplementary Table 8. Candidate neoantigens and HLA class I predicted binding affinities for WHIM35.
Authors: Xiuli Zhang, Samuel Kim, Jasreet Hundal, John M. Herndon, Shunqiang Li, Allegra A. Petti, Savas D. Soysal, Lijin Li, Mike D. McLellan, Jeremy Hoog, Tina Primeau, Nancy Myers, Tammi L. Vickery, Mark Sturmoski, Ian S. Hagemann, Chris A. Miller, Matthew J. Ellis, Elaine R. Mardis, Ted Hansen, Timothy P. Fleming, S. Peter Goedegebuure, William E. Gillanders
Language: English
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
OpenAlex ID: W4362568458