Supplemental Figures 1-5 from Calcium Sensor, NCS-1, Promotes Tumor Aggressiveness and Predicts Patient Survival
Year: 2023
Type: supplementary-materials
Abstract: Figure 1: NCS-1 and its Known Binding Partners: This web diagram illustrates the binding partners of NCS-1. Figure 2: Assessment of the effect of NCS-1 on Motility: Representative photomicrographs from scratch motility assays for A. Figure 3: NCS-1 May Promote Tumor Aggressiveness by Altering Invasion and Chemotaxis: Representative photomicrographs from Transwell invasion assays show that overexpression of NCS-1 increases invasion in both A. MCF-7 and B. MB-231 cell lines. Figure 4: NCS-1 May Promote Tumor Aggressiveness by Altering Adhesion: Representative images for Collagen IV cell-adhesion assay for A. MCF-7 and B. MB-231 cell lines. Figure 5: Assessment of NCS-1 in Normal Breast Tissue. A. AQUA scores for NCS-1 in the tumor mask (y-axis) for each individual patient (x-axis). B. Normal distribution of NCS-1 AQUA scores for collective normal breast tissue cohort.
Language: English
Topic: S100 Proteins and Annexins
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: gold
OpenAlex ID: W4362592181