Work

Supplementary Movie 3A from Constitutive K-RasG12D Activation of ERK2 Specifically Regulates 3D Invasion of Human Pancreatic Cancer Cells via MMP-1

Year: 2023

Type: supplementary-materials

Abstract: AVI file - 4MB, Real-time imaging of E6/E7/Ras PDECs plus sh-MMP-1 in 3D show a trabelcular spreading pattern with limited invadapodial protrusions into the ECM and increased horizontal spreading over 30 m.

DOI: 10.1158/1541-7786.22517878

Authors: Gregory P. Botta, Mauricio J. Reginato, Maximilian Reichert, Anil K. Rustgi, Peter I. Lelkes

Language: English

Topic: Protein Kinase Regulation and GTPase Signaling

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4362596764

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