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Supplementary Figures 1-4 from Notch Reporter Activity in Breast Cancer Cell Lines Identifies a Subset of Cells with Stem Cell Activity

Year: 2023

Type: supplementary-materials

Abstract: Supplemental Figure 1. Notch4 mRNA expression correlates with Notch ligands and downstream effectors; Supplemental Figure 2. A schematic outline of experimental procedures; Supplemental Figure 3. A single Notch+ cell has the capacity to generate tumors that represents the initial heterogeneity; Supplemental Figure 4. Evaluation of tumor growth following the treatment of animals with GSI, Docetaxel or combination treatments.

DOI: 10.1158/1535-7163.22502347

Authors: Rosemarie C. D'Angelo, Maria Ouzounova, April Davis, Daejin Choi, Stevie M. Tchuenkam, Gwangil Kim, Tahra Luther, Ahmed A. Quraishi, Yasin Senbabaoglu, Sarah J. Conley, Shawn G. Clouthier, Khaled A. Hassan, Max S. Wicha, Hasan Korkaya

Language: English

Topic: Cancer Cells and Metastasis

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

Open Access status: gold

OpenAlex ID: W4362609449

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