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Figure S1-S6 from Cisplatin Increases Sensitivity to FGFR Inhibition in Patient-Derived Xenograft Models of Lung Squamous Cell Carcinoma

Year: 2023
Type: other
Abstract: Supplementary Fig. S1. Generation of patient-derived xenografts from surgery and biopsy specimens of non small cell lung cancer Supplementary Fig. S2. Squamous cell carcinoma patient-derived xenografts recapitulate the genomic phenotype of patients'' tumors Supplementary Fig. S3. Analysis of biomarkers of response to FGFR inhibition Supplementary Fig. S4. High FGFR1 RNA expression does not predict patient outcome Supplementary Fig. S5. PIK3CA amplification does not predict response to PI3K inhibitors Supplementary Fig. S6. FGFR targeted therapy in FGFR inhibitor resistant tumors does not increase cisplatin sensitivity
DOI: 10.1158/1535-7163.22508316
Authors: Clare E. Weeden, Aliaksei Z. Holik, Richard J. Young, Stephen B. Ma, Jean-Marc Garnier, Stephen B. Fox, Phillip Antippa, Louis B. Irving, Daniel P. Steinfort, Gavin M. Wright, Prudence A. Russell, Matthew E. Ritchie, Christopher J. Burns, Benjamin Solomon, Marie-Liesse Asselin-Labat
Language: English
Field: Medicine
Open Access status: gold
OpenAlex ID: W4362610264
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