Supplementary Tables 1 - 5 from PP6C Hotspot Mutations in Melanoma Display Sensitivity to Aurora Kinase Inhibition
Year: 2023
Type: supplementary-materials
Abstract: PDF file - 151K, Supplemental Table 1. mutations found in NYU cohort and previously discovered by Hodis et al; and Krauthammer et al; Supplemental Table 2. Breslow-Day test of homogeneity for association between PP6C, BRAF, or NRAS mutations in Primary and Metastatic patients respectively. Supplemental Table 3. Bbaseline characteristics and prognostic factors by PP6C mutation status in primary and metastatic patients. Supplemental Table 4: PP6C, BRAF and NRAS mutation allele:wild-type allele ratios. Supplemental Table 5. Correlation of PP6R binding and Aurora A Kinase phosphorylation(primary patients only).
Language: English
Topic: Melanoma and MAPK Pathways
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: gold
OpenAlex ID: W4362612534