Data Supplement from Hypoxia Provokes Base Excision Repair Changes and a Repair-Deficient, Mutator Phenotype in Colorectal Cancer Cells
Year: 2023
Type: other
Abstract: Supplementary Figure 1. (A) There is no effect on cell proliferation in RKO cells. (B) There is no effect on S-phase fraction in RKO and paired HCT116 cells. (C) 50-65% Clonogenic cell survival in RKO and paired HCT116 cells. (D) BER mRNA expression is unchanged in RKO cells. qRT-PCR analyses show no significant effects of prolonged hypoxia (72 h x 0.2% O2) on the mRNA levels of selected BER genes in RKO cells. Carbonic anhydrase IX (CAIX) is shown as a positive control for hypoxia.
Language: English
Topic: DNA Repair Mechanisms
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: gold
OpenAlex ID: W4362613265