Supplementary Materials, Supplementary Figures 1-5 from Clinical and Functional Significance of TP53 Exon 4–Intron 4 Splice Junction Variants
Year: 2023
Type: supplementary-materials
Abstract: S1. Proband pedigrees. S2. TP53 status as determined by Multiplex Ligation Probe Amplification for Saos-2 and H1299 cell lines. S3. TP53 altering splice variants in the (a) IARC database (b) PCGP database. (c) Total germline TP53 variants observed in IPACTR and COG studies Circles represent number of cases. S4. Chromatogram representing the constructs for the TP53 variants included in this study. S5. p53 Immunostaining of pediatric tumors associated with germline mutations at codon 125 and surrounding sequences.
Authors: Emilia M. Pinto, Kara N. Maxwell, Hadeel Halalsheh, Aaron Phillips, Jacquelyn Powers, Suzanne MacFarland, Michael F. Walsh, Kelsey Breen, Maria N. Formiga, Richard Kriwacki, Kim E. Nichols, Roya Mostafavi, Jinling Wang, Michael R. Clay, Carlos Rodriguez-Galindo, Raul C. Ribeiro, Gerard P. Zambetti
Language: English
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
OpenAlex ID: W4362616025