Figure S3 from Immune-Checkpoint Blockade Opposes CD8+ T-cell Suppression in Human and Murine Cancer
Year: 2023
Type: other
Abstract: Supplementary Figure 3 . CD3+ CD8+ PD-1+ Tim-3+ and CD3+ CD8+ CD27- CD28- cells were sorted from SCCHN tissue. Purified cells were then used in an in vitro suppression assays with autologous T cells. Ratios indicate the number of suppressors to responders. Controls are using equivalent numbers of responder cells alone. Responders were labeled with CFSE. BrdU was added during the final 18 hours of culture. Indicated data are representative of at least three independent experiments. Error bars represent SD of replicate wells for each condition.
Language: English
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
OpenAlex ID: W4362618914