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Figure S3 from Cell-free DNA Predicts Prolonged Response to Multi-agent Chemotherapy in Pancreatic Ductal Adenocarcinoma

Year: 2023

Type: other

Abstract: Supplemental Figure 3. Post-treatment KRAS and change in KRAS VAF following treatment. To determine whether KRAS VAF following 2 cycles of treatment or the change in KRAS VAF from pre-treatment to after 2 cycles of treatment is correlated with CT response at 2 months, each patient’s CT response to treatment was plotted against KRAS VAF and calculated Spearman’s rank correlation coefficient. There was a significant correlation between post-treatment KRAS VAF and CT response (panel A) (R=0.58) and change in KRAS and CT response (panel B) (R=0.59)

DOI: 10.1158/2767-9764.22545302

Authors: Eric S. Christenson, Su Jin Lim, Jennifer Durham, Ana De Jesus-Acosta, Katherine Bever, Daniel Laheru, Amy Ryan, Parul Agarwal, Robert B. Scharpf, Dung T. Le, Hao Wang

Language: English

Topic: Pancreatic and Hepatic Oncology Research

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4362619782

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