Work

Figure S2 from Cell-free DNA Predicts Prolonged Response to Multi-agent Chemotherapy in Pancreatic Ductal Adenocarcinoma

Year: 2023

Type: other

Abstract: Supplemental Figure 2. Scatterplots comparing baseline RECIST tumor measurements with baseline cell-free DNA (cfDNA) biomarkers. To determine the relationship between baseline tumor mutational variant allele frequency (VAFs) and total tumor burden we compared baseline tumor burden as measured by RECIST measurements of evaluable lesions (sum of diameters in mm) with KRAS (panel A) and TP53 (panel B) VAFs for these tumors at the same time point. These data demonstrated no statistically significant relationship between baseline cfDNA VAF levels and RECIST measurements on CT scan.

DOI: 10.1158/2767-9764.22545305

Authors: Eric S. Christenson, Su Jin Lim, Jennifer Durham, Ana De Jesus-Acosta, Katherine Bever, Daniel Laheru, Amy Ryan, Parul Agarwal, Robert B. Scharpf, Dung T. Le, Hao Wang

Language: English

Topic: Cancer Genomics and Diagnostics

Subfield: Cancer Research

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4362619792

Cites:

Cited by:

Related to: 10