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Supplemental Tables 1-4 from Characterization of a Dual Rac/Cdc42 Inhibitor MBQ-167 in Metastatic Cancer

Year: 2023

Type: supplementary-materials

Abstract: Supplemental Table 1: Effect of MBQ-167 on Rho GTPase activity (Active Rho GTPase/Total Rho GTPase) following 24 h in MDA-MB-231 cells, relative to vehicle (=1); Supplemental Table 2: Effect of MBQ-167 on Rac activity (Active Rac/Total Rac) following 24 h in MCF-7 cells; Supplemental Table 3: Optimal %Treated (T)/Control (C) for mammary fat pad tumor growth for EHop-167 treated nude mice; Supplemental Table 4: Tumor growth delay for EHop-167-treated mice

DOI: 10.1158/1535-7163.22504737

Authors: Tessa Humphries-Bickley, Linette Castillo-Pichardo, Eliud Hernandez-O’Farrill, Luis D. Borrero-Garcia, Ingrid Forestier-Roman, Yamil Gerena, Manuel Blanco, Michael J. Rivera-Robles, José R. Rodriguez-Medina, Luis A. Cubano, Cornelis P. Vlaar, Suranganie Dharmawardhane

Language: English

Topic: Protein Kinase Regulation and GTPase Signaling

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4362609799

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