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Figure S1-S4 from Evaluating the Mechanism and Therapeutic Potential of PTC-028, a Novel Inhibitor of BMI-1 Function in Ovarian Cancer

Year: 2023

Type: other

Abstract: Figure S1: Synthesis of PTC-028; Figure S2: Specificity of PTC-028 towards high BMI-1 expressing cells; Figure S3: PTC-028 induces caspase-dependent apoptosis; Figure S4: Pharmacokinetics of PTC-028 after a single oral dose of either 10 mg/kg or 20mg/kg to CD-1 mice

DOI: 10.1158/1535-7163.22505569

Authors: Anindya Dey, Xunhao Xiong, Aleia Crim, Shailendra Kumar Dhar Dwivedi, Soumyajit Banerjee Mustafi, Priyabrata Mukherjee, Liangxian Cao, Nadiya Sydorenko, Ramil Baiazitov, Young-Choon Moon, Melissa Dumble, Thomas Davis, Resham Bhattacharya

Language: English

Topic: Ovarian cancer diagnosis and treatment

Subfield: Reproductive Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4362609897

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