Supplemental Tables 1-5, Supplemental Figure 1-2 from Breast Cancer Risk–Associated SNPs in the mTOR Promoter Form De Novo KLF5- and ZEB1-Binding Sites that Influence the Cellular Response to Paclitaxel
Year: 2023
Type: supplementary-materials
Abstract: Table S1. Frequencies of mTOR promoter polymorphisms in patients with breast cancer and healthy controls Table S2. Frequency distribution of mTOR haplotypes and their associations with the risk of developing breast cancer Table S3. Association of mTOR haplotypes with clinicopathological parameters in patients with breast cancer Table S4. Association of mTOR polymorphisms with clinicopathological parameters in patients with breast cancer Table S5. Association of mTOR polymorphisms with therapeutic response to neoadjuvant chemotherapy (n=131) Figure S1. The impact of forced expression of pcmTOR-Ht1 or pcmTOR-Ht2 on cell proliferation and cell cycle and chemoresistance to PTX in MCF7/PTX cells. Figure S2. Plasma concentration of PTX detection by using UPLC-MS/MS method.
Authors: Qiuchen Chen, Xiaolan Deng, Xiaoyun Hu, Shu Guan, Miao He, Yilin Wang, Binbin Wei, Jing Zhang, Haishan Zhao, Weifan Yao, Feng Jin, Yong Liu, Jianjun Chen, Olufunmilayo I. Olapade, Huizhe Wu, Minjie Wei
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: gold
OpenAlex ID: W4362624296