Supplementary Figures 1-12 from Mitochondrial DNA Mutations are Associated with Ulcerative Colitis Preneoplasia but Tend to be Negatively Selected in Cancer
Year: 2023
Type: supplementary-materials
Abstract: Figure S1.Histology of UC colon tissue. Figure S2. Clonal expansions Figure S3. Clonal and Subclonal Mutations by Biopsy Figure S4. Association between mutation number and total DCS nucleotides sequenced. Figure S5. Association of Clonal and Subclonal Mutations with Clinical Variables. Figure S6. MAF of individual clonal and subclonal mutations. Figure S7. C>A Mutation Frequencies by Biopsy. Figure S8. Association of Very Low Frequency Mutations with clinical variables. Figure S9. Mutation Signature by Mutation Type. Figure S10. VLF transitions and transversions by mtDNA Region and biopsy type. Figure S11. VLF mutation frequency and Gene Size. Figure S12. Model of mitochondrial mutation progression during UC carcinogenesis.
Language: English
Subfield: Pathology and Forensic Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: gold
OpenAlex ID: W4362624297