Work

Supplementary Figures 1-7 from TCF21 Promotes Luminal-Like Differentiation and Suppresses Metastasis in Bladder Cancer

Year: 2023

Type: supplementary-materials

Abstract: Supplemental Figure 1. Gene set enrichment analysis. Supplemental Figure 2. TCF21 expression analysis. Supplemental Figure 3. TCF21 expression in cell lines. Supplemental Figure 4. Loss-of-function and gain-of-function studies of TCF21 Supplemental Figure 5. CD24 and CD44 expression in TCF21 OE UM-UC3 and UM-UC13 cells. Supplemental Figure 6. GSEA analysis of common pathways altered between the three cell lines. Supplemental Figure 7. Heatmap of hierarchical clustering of luminal markers showing differential expression after TCF21 upregulation in UC13 LN (A) and UC13 MET (B) cells.

DOI: 10.1158/1541-7786.22517344.v1

Authors: Sharada Mokkapati, Sima P. Porten, Vikram M. Narayan, Amy H. Lim, Isuru S. Jayaratna, Beat Roth, Tiewei Cheng, Neema Navai, Matthew Wszolek, Jonathan Melquist, Ganiraju Manyam, Woonyoung Choi, Bradley Broom, Shanna Pretzsch, Bogdan Czerniak, David J. McConkey, Colin P. N. Dinney

Language: English

Topic: Bladder and Urothelial Cancer Treatments

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4362624676

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