Work

Figure S6 from BRCA1/MAD2L1 Deficiency Disrupts the Spindle Assembly Checkpoint to Confer Vinorelbine Resistance in Mesothelioma

Year: 2023

Type: other

Abstract: Cyclin B expression is not altered after silencing of BRCA1 or treatment with vinorelbine. Western blots showing expression of cyclin B in MSTO-211H and REN cells 24 hours after silencing, and treatment of parental and resistant cells with vinorelbine 50nM (REN/RVR) or 100 nM (MSTO-211H/MVR) for 48 hours.

DOI: 10.1158/1535-7163.22521780

Authors: Sara Busacca, Laura O'Regan, Anita Singh, Annabel J. Sharkey, Alan G. Dawson, Joanna Dzialo, Aimee Parsons, Neelam Kumar, Laurel M. Schunselaar, Naomi Guppy, Apostolos Nakas, Michael Sheaff, Aaron S. Mansfield, Sam M. Janes, Paul Baas, Andrew M. Fry, Dean A. Fennell

Language: English

Topic: Microtubule and mitosis dynamics

Subfield: Cell Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4362624951

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