Work

Supplementary Figures 1 - 6 from A Cross-Species Analysis in Pancreatic Neuroendocrine Tumors Reveals Molecular Subtypes with Distinctive Clinical, Metastatic, Developmental, and Metabolic Characteristics

Year: 2023

Type: supplementary-materials

Abstract: Supplementary Figure 1. NMF analysis of PanNET miR expression and its validation. Supplementary Figure 2. NMF analysis of PanNET gene expression and its validation. Supplementary Figure 3. Cross-species analysis of gene expression subtypes in human and mouse PanNETs. Supplementary Figure 4. ENPP2 and INS mRNA expression in human PanNET subtypes as assessed using human PanNET core clinical gene expression microarray dataset. Supplementary Figure 5. Comparison of mouse PanNET subtypes to microdissected invasive IT vs. non-invasive IC2 of mouse PanNET tumors: Relationship to PanNET histotypes and progenitor gene signatures. Supplementary Figure 6. Metabolic profiles of IT and MLP cell lines.

DOI: 10.1158/2159-8290.22531151

Authors: Anguraj Sadanandam, Stephan Wullschleger, Costas A. Lyssiotis, Carsten Grötzinger, Stefano Barbi, Samantha Bersani, Jan Körner, Ismael Wafy, Andrea Mafficini, Rita T. Lawlor, Michele Simbolo, John M. Asara, Hendrik Bläker, Lewis C. Cantley, Bertram Wiedenmann, Aldo Scarpa, Douglas Hanahan

Language: English

Topic: Neuroendocrine Tumor Research Advances

Subfield: Epidemiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4362531519

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