Work

Figure S1 from Immune-Checkpoint Blockade Opposes CD8+ T-cell Suppression in Human and Murine Cancer

Year: 2023

Type: other

Abstract: Supplementary Figure 1 A. Dot plots displaying ungated staining of CD8+ CD27/CD28- T cells FACS sorted from human SCCHN tumor tissue and used in Figure 1D. B. Staining of CD8+ PD-1+ Tim-3+ T cells FACS sorted from dissociated human SCCHN tumor tissue and used in Figure 1E. C. Staining of CD8+ T cells purified from dissociated TC-1 tumors by magnetic bead positive selection using the indicated antibodies. D. Ungated staining of the PD-1+/Tim-3+, PD-1+/Tim-3-, and PD-1-/Tim-3- cells FACS sorted from CD3+ CD8+ T cells in dissociated TC-1 tumors.

DOI: 10.1158/2326-6066.22539566.v1

Authors: Lukas W. Pfannenstiel, C. Marcela Diaz-Montero, Ye F. Tian, Joseph Scharpf, Jennifer S. Ko, Brian R. Gastman

Language: English

Topic: Cancer Immunotherapy and Biomarkers

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4362629094

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