Work

Fig FS3 from Misaligned Chromosomes are a Major Source of Chromosomal Instability in Breast Cancer

Year: 2023

Type: other

Abstract: Figure S3. Lagging chromosomes in breast cancer are primarily mitotic in origin. A-B. Images of lagging chromosomes lacking a centromere, which are likely to occur due to premitotic defects (A) or containing their centromere, which are likely to arise due to mitotic defects (B). C. Quantification of lagging chromosomes in 8 primary tumors showing acentric (ACA-) fragments are less frequent than lagging chromosomes containing centromeres. Data represent mean +/- SD.

DOI: 10.1158/2767-9764.22546127.v1

Authors: John B. Tucker, Sarah C. Bonema, Rebeca García-Varela, Ryan A. Denu, Yang Hu, Stephanie M. McGregor, Mark E. Burkard, Beth A. Weaver

Language: English

Topic: Microtubule and mitosis dynamics

Subfield: Cell Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4362630552

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