Supplementary Figures 1 - 6 from Nuclear Expression of β-Catenin Promotes RB Stability and Resistance to TNF-Induced Apoptosis in Colon Cancer Cells
Year: 2023
Type: supplementary-materials
Abstract: PDF file - 2529K, S1 Similar levels of TUNEL-positive cells were observed in the splenic tissue sections from Rb+/+ and RbMI/MI mice at 24 hr after PBS (Veh) or TNF-α i.p. injection. Scale bar: 50 μm. **p<0.01, error bars: SD. S2 Characterization of colonic tumors induced by AOM/DSS in Rb+/+ and RbMI/MI mice. S3 β-catenin exon-3 sequencing, E-cadherin staining, TNF-induced IκB degradation and RB cleavage in colon cancer cells. S4 RB knockdown enhanced TNF/CHX induced apoptosis in HCT116 cells. S5 Effects of GSK-3β inhibitor AR on HCT116 cells S6 Co-immunoprecipiation of RB and β-catenin and in vitro Caspase Cleavage of RB
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: gold
OpenAlex ID: W4362596406