Figure S1 from An Orally Available Tubulin Inhibitor, VERU-111, Suppresses Triple-Negative Breast Cancer Tumor Growth and Metastasis and Bypasses Taxane Resistance
Year: 2023
Type: other
Abstract: Figure S1 shows that VERU-111 inhibits TNBC cell migration and invasion at 16 nM. (A) Representative images of migration assays showing MDA-MB-231 (upper panel) and MDA-MB-468 (lower panel) cells treated with VERU-111 (16 nM) for 24 h and 48 h, respectively, that have migrated through transwell membrane inserts. (B) Representative images of invasion assays showing MDA-MB-231 (upper panel) and MDA-MB-468 (lower panel) cells treated with VERU-111 (16 nM) for 24 h and 48 h, respectively, using Matrigel-coated transwell membrane inserts. All data are presented as the grand mean {plus minus} SEM of three independent experiments, with p-values determined relative to the Control group (normalized to 100%), scale bar = 100 µm.
Language: English
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
OpenAlex ID: W4362639701