Work

Intrinsic Resistance to Colistin in the Genus Hafnia

Year: 2023

Type: article

Abstract: A bacterial species is considered to be intrinsically resistant to an antimicrobial when nearly all of the wild-type isolates (i.e., those without acquired resistance) exhibit minimum inhibitory concentration (MIC) values that are sufficiently high such that susceptibility testing is unnecessary, and that the antimicrobial should not be considered for therapy. Accordingly, knowledge of intrinsic resistance influences both the selection of treatment regimens and the approach to susceptibility testing in the clinical laboratory, where unexpected results also facilitate the recognition of microbial identification or susceptibility testing errors.

Source: Journal of Clinical Microbiology

DOI: 10.1128/jcm.01326-22

Authors: Sarah E. Turbett, Ryan A. Bronson, Colin J. Worby, Graham E. G. McGrath, Emily Hodgkins, Margaret Becker, Barbara Belford, Lucyna Kogut, Elizabeth Oliver, Edward T. Ryan, Regina C. LaRocque, Ashlee M. Earl, Virginia M. Pierce

Institutions: Harvard University, Massachusetts General Hospital, Broad Institute

Language: English

Topic: Antibiotic Resistance in Bacteria

Subfield: Molecular Medicine

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: U.S. Department of Health and Human Services, Massachusetts General Hospital, Broad Institute, Centers for Disease Control and Prevention Foundation, National Institutes of Health, Centers for Disease Control and Prevention, National Institute of Allergy and Infectious Diseases

Awards: Advancing genomic, transcriptomic and functional approaches to combat globally important and emerging pathogens, G2898696312, G3708211351, GLOBAL TRAVEPINET (GTEN): U.S. TRAVELERS? HEALTH RESEARCH, SURVEILLANCE, COMMUNICATION AND OUTREACH NETWORK, GLOBAL TRAVEPINET (GTEN): THE HEADING HOME HEALTHY PROGRAM AND GLOBAL TRAVELERS' HEALTH NATIONAL RESEARCH CENTER CONSORTIUM, GUIDANCE AND OUTREACH PR, G8014130074

OpenAlex ID: W4362657682

FWCI: 0.243

Cites: 31

Cited by: 3

Related to: 10