Signal attenuation-compensated projection-resolved OCT angiography
Year: 2023
Type: article
Abstract: Projection artifacts are a significant limitation of optical coherence tomographic angiography (OCTA). Existing techniques to suppress these artifacts are sensitive to image quality, becoming less reliable on low-quality images. In this study, we propose a novel signal attenuation-compensated projection-resolved OCTA (sacPR-OCTA) algorithm. In addition to removing projection artifacts, our method compensates for shadows beneath large vessels. The proposed sacPR-OCTA algorithm improves vascular continuity, reduces the similarity of vascular patterns in different plexuses, and removes more residual artifacts compared to existing methods. In addition, the sacPR-OCTA algorithm better preserves flow signal in choroidal neovascular lesions and shadow-affected areas. Because sacPR-OCTA processes the data along normalized A-lines, it provides a general solution for removing projection artifacts agnostic to the platform.
Source: Biomedical Optics Express
DOI: 10.1364/boe.483835
Institution: Oregon Health & Science University
Language: English
Subfield: Biomedical Engineering
Field: Engineering
Domain: Physical Sciences
Open Access status: gold
Estimated APC paid: $1,913
Awards: G1101846420, Visible-light OCT angiography, velocimetry, and oximetry for characterizing retinal vascular alterations in glaucoma, G9000060460, G9000062576, G9000108527, G9000127190, G9000149203, Functional and Structural Optical Coherence Tomography for Glaucoma, Ophthalmology Core Facility
OpenAlex ID: W4362732972