Work

Kinetic characterization of an efficient cocaine hydrolase against toxic metabolites of cocaine

Year: 2023

Type: article

Source: Organic & Biomolecular Chemistry

DOI: 10.1039/d3ob00374d

Authors: Max Zhan, Shurong Hou, Linyue Shang, Xiabin Chen, Chang-Guo Zhan, Fang Zheng

Institution: University of Kentucky

Language: English

Topic: Enzyme Catalysis and Immobilization

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: closed

Funders: National Heart, Lung, and Blood Institute, National Institute on Drug Abuse

Awards: Comparative Effectiveness of Health System vs. Multilevel Interventions to Reduce Hypertension Disparities, G5154985870, Development of a Cocaine-Metabolizing Enzyme for Drug Overdose Treatment, Development of a Long-acting Enzyme Therapy for Treatment of Cocaine Abuse, Validation of ghrelin hydrolysis as an effective approach to treatment of substance use disorders, Long-lasting cocaine-metabolizing enzyme for cocaine addiction treatment, Redesign of Butyrylcholinesterase for Cocaine Metabolism, Development of Long-acting Cocaine Hydrolase as a Treatment for Cocaine Abuse

OpenAlex ID: W4364323353

FWCI: 0.355

Cites: 55

Cited by: 4

Related to: 10