Changes in Diet Quality from Pregnancy to 6 Years Postpregnancy and Associations with Cardiometabolic Risk Markers
Year: 2023
Type: article
Study design: Observational Study
Abstract: Adopting a healthy diet during and after pregnancy is important for women's cardiometabolic health. We related changes in diet quality from pregnancy to 6 years postpregnancy to cardiometabolic markers 8 years postpregnancy. In 652 women from the GUSTO cohort, we assessed dietary intakes at 26-28 weeks' gestation and 6 years postpregnancy using 24 h recall and a food frequency questionnaire, respectively; diet quality was scored using a modified Healthy Eating Index for Singaporean women. Diet quality quartiles were derived; stable, large/small improvement/decline in diet quality as no change, >1 or 1 quartile increase/decrease. Fasting triglyceride (TG), total-, high- and low-density-lipoprotein cholesterol (TC, HDL- and LDL-C), glucose and insulin were measured 8 years postpregnancy; homeostatic model assessment for insulin resistance (HOMA-IR) and TG: HDL-C ratio were derived. Linear regressions examined changes in diet quality quartiles and cardiometabolic markers. Compared to a stable diet quality, a large improvement was associated with lower postpregnancy TG [-0.17 (-0.32, -0.01) mmol/L], TG: HDL-C ratio [-0.21 (-0.35, -0.07) mmol/L], and HOMA-IR [-0.47 (-0.90, -0.03)]; a large decline was associated with higher postpregnancy TC and LDL-C [0.25 (0.02, 0.49); 0.20 (0.004, 0.40) mmol/L]. Improving or preventing a decline in diet quality postpregnancy may improve lipid profile and insulin resistance.
Source: Nutrients
DOI: 10.3390/nu15081870
Institutions: Agency for Science, Technology and Research, Singapore Institute for Clinical Sciences, University Hospital Southampton NHS Foundation Trust, NIHR Southampton Biomedical Research Centre, University of Southampton, KK Women's and Children's Hospital, Duke-NUS Medical School, National University of Singapore, National University Health System, University of Helsinki
Language: English
Topic: Nutritional Studies and Diet
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $2,892
Awards: Children of UPBEAT: a study of cardiovascular function in 10-year-old children of obese women who participated in an antenatal lifestyle intervention, G1917706474, Interdisciplinary Research Network on Early Adversity & Later Life Reversibility, G3424013768, NIHR Senior Investigator Award, G3873828540, G427574963, NIHR Senior Investigator Award, G7388601084, Nutrition, Development and Lifelong Health: Studies in European Populations
OpenAlex ID: W4365448568
