Work

Cutaneous graft-versus-host disease within chronic photodamaged skin: A case series demonstrating role for topical 5-fluorouracil

Year: 2023

Type: article

Study design: Case Report

Abstract: Chronic graft-versus-host disease (cGVHD) is a major limitation to hematopoietic stem cell transplantation (HSCT), with a high mortality rate and significant financial burden on the U.S. health care system, with estimated treatment cost of 527 million USD per year.1-3 The skin is the most common affected organ in cGVHD, present in >90% of cases4; additionally, it is often the first organ to be affected, foreshadowing disease in other systems.5

Source: JAAD Case Reports

DOI: 10.1016/j.jdcr.2023.03.023

Authors: Ashley N. Gray, Christina Avila, Catherine G. Chung, Lucia Seminario-Vidal, Alice Mims, Brittany Dulmage, Karilyn Larkin, Hannah Choe, Samantha Jaglowski, Sumithira Vasu, Benjamin H. Kaffenberger

Institutions: The Ohio State University Wexner Medical Center, The Ohio State University, Riverside Methodist Hospital, Moffitt Cancer Center, The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute

Language: English

Topic: Hematopoietic Stem Cell Transplantation

Subfield: Hematology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $675

Funder: Ohio State University

OpenAlex ID: W4366525470

FWCI: 0.886

Cites: 23

Cited by: 5

Related to: 10