Work

C. elegans dkf-1 (Protein Kinase D1) mutants have age-dependent defects in locomotion and neuromuscular transmission

Year: 2023

Type: article

Abstract: , show an acceleration in age-dependent decline of locomotion rate and an alteration to age-dependent changes in aldicarb sensitivity. These effects could be explained by a pre- or post-synaptic function of the protein kinase as the animal ages.

Source: PubMed

DOI: 10.17912/micropub.biology.000800

Authors: James R. Johnson, Jeff W. Barclay

Institution: University of Liverpool

Language: English

Topic: Genetics, Aging, and Longevity in Model Organisms

Subfield: Aging

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

Funders: Wellcome Trust, National Institutes of Health, National Center for Research Resources

OpenAlex ID: W4366821590