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Remote Aerosol SARS-CoV-2 Transmission from Clinical COVID Patients to Rodent Sentinels

Year: 2023

Type: preprint

Abstract: We performed studies investigating the feasibility of human to animal (H2A) model system to test whether patient generated respiratory bioaerosols hold infective capacity when traversing long distance airborne transport within the built environment. South African patients, clinically confirmed by facemask sampling to be exhaling SARS-CoV-2 genomic sequence, were recruited and housed for multiple days in a clinical ward with a uniquely designed building ventilation system continuously channeling exhaust airflow to individual microisolator animal caging units located proximal but segregated from clinic space (University of Pretoria AIR facility).

DOI: 10.31219/osf.io/cre2w

Authors: Edward Anthony Nardell, Chad J Roy, Michael Barer, Veronica Ueckermann

Institution: Harvard University

Language: English

Topic: Infection Control and Ventilation

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W4367184310

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