Work

Kratom-induced acute liver injury: A case study and the importance of herbal supplement regulation

Year: 2023

Type: article

Abstract: Alternative medicine supplements have become the second most common cause of drug-induced liver injury (DILI) in the US. Kratom is a herbal supplement that is popular for its psychotropic and opioid-like activity. It has become increasingly available in western countries, which often have no specific regulations on its use. However, reports of adverse events linked to kratom use have been increasing; it has been implicated in acute liver injury (mostly cholestatic), acute liver failure, organ dysfunction, toxicity, coma, seizures, and death. Herein, we aim to increase healthcare provider and public awareness of the risks posed by kratom and ultimately support increased regulation of its use.

Source: Journal of Hepatology

DOI: 10.1016/j.jhep.2023.04.026

Authors: Katerina Roma, Salman Mohammed, Blake Sieck, Katrina Naik, Shahid Wahid

Institution: University of Nevada, Las Vegas

Language: English

Topic: Drug-Induced Hepatotoxicity and Protection

Subfield: Pharmacology

Field: Pharmacology, Toxicology and Pharmaceutics

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $4,950