Work

Chimeric RNAs and their implication in prostate cancer

Year: 2023

Type: article

Abstract: •Chimeric ribonucleic acids (RNAs) form through gene fusion, trans-splicing, or cis-splicing between adjacent genes (cis-SAGe) mechanisms•Chimeric RNAs influence prostate cancer (PCa) progression by acting as long noncoding RNAs (lncRNAs) or circular RNAs (circRNAs), coding fusion proteins, and misregulating parental genes•Misregulated chimeric RNAs represent a novel repertoire for biomarkers and targets for PCa therapy.

Source: Cancer Pathogenesis and Therapy

DOI: 10.1016/j.cpt.2023.04.003

Authors: Hui Li, Qiong Wang

Institutions: University of Virginia, Nanfang Hospital, Southern Medical University

Language: English

Topic: Cancer-related molecular mechanisms research

Subfield: Cancer Research

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,100