Work

Important considerations regarding the widespread use of doxycycline chemoprophylaxis against sexually transmitted infections

Year: 2023

Type: article

Abstract: Rates of sexually transmitted infections (STIs) continue to rise across the world and interventions are essential to reduce their incidence. Past and recent studies have indicated this may be achieved using doxycycline post-exposure prophylaxis (PEP) and this has sparked considerable interest in its use. However, many unanswered questions remain as to its long-term effects and particularly potentially negative impact on human microbiomes and antimicrobial resistance among STIs, other pathogens, and commensals. In this review, we discuss seven areas of concern pertaining to the widespread use of doxycycline PEP.

Source: Journal of Antimicrobial Chemotherapy

DOI: 10.1093/jac/dkad129

Authors: Fabian Yuh Shiong Kong, Chris Kenyon, Magnus Unemo

Institutions: The University of Melbourne, University of Cape Town, Instituut voor Tropische Geneeskunde, Örebro University, University College London

Language: English

Topic: Reproductive tract infections research

Subfield: Microbiology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $3,268