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Supplementary Figure S1 from Epidermal growth factor receptor inhibition by cetuximab modulates hypoxia and interferon response genes in head and neck squamous cell carcinoma

Year: 2023

Type: supplementary-materials

Abstract: (A, B) Heatmap of molecular subgroups in two different HNSCC datasets (A) TCGA and (B) CPTAC. RNA expression data was z-normalized, each row represents a single gene in the hypoxia-immune signature gene list, each column represents a patient sample. Samples were reordered according to its molecular subgroup: Immune (blue), Mixture (black) and Hypoxia (red). (C) Kaplan–Meier survival plots for overall survival stratified according to the hypoxia-immune signature for TCGA (n = 518) HNSCC patient cohorts.

DOI: 10.1158/2767-9764.22761551.v1

Authors: Ritu Chaudhary, Robbert J.C. Slebos, Leenil C. Noel, Feifei Song, Maria I. Poole, Dirk S Hoening, Juan C. Hernandez-Prera, Jose R Conejo-Garcia, Jose Alejandro Guevara, Xuefeng Wang, Mengyu Xie, Aik Choon Tan, Christine H. Chung

Language: English

Topic: Head and Neck Cancer Studies

Subfield: Otorhinolaryngology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4368372747

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