Work

Autophagy regulates anti-angiogenic property of lenvatinib in thyroid cancer.

Year: 2023

Type: article

Abstract: . In conclusion, lenvatinib inhibited cell viability and induced apoptosis and autophagy in human PTC cells. Significantly, the combination of lenvatinib and autophagy inhibition may represent a novel and effective treatment option for PTC, which may be able to overcome drug resistance.

Source: PubMed Central

Authors: Lingbin Xue, Zhongqin Gong, Alexander C Vlantis, Jason Yk Chan, Katie Meehan, Charles Andrew van Hasselt, Dongcai Li, Xianhai Zeng, Minghui Wei, Michael Cf Tong, George G Chen

Institutions: Chinese University of Hong Kong, Prince of Wales Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College

Language: English

Topic: Thyroid Cancer Diagnosis and Treatment

Subfield: Endocrinology, Diabetes and Metabolism

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Natural Science Foundation of China, Chinese University of Hong Kong

Award: G4194245815

OpenAlex ID: W4376224870

FWCI: 2.426

Cites: 37

Cited by: 15

Related to: 10