Maternal and fetal mitochondrial gene dysregulation in hypertensive disorders of pregnancy
Year: 2023
Type: article
Study design: Observational Study
Abstract: This study identifies aberrant maternal and fetal expression of mitochondrial genes in pregnancies with gestational hypertension and preeclampsia. Mitochondrial gene dysregulation may be a common etiological factor contributing to the development of de novo hypertension in pregnancy-associated hypertensive disorders.
Source: Physiological Genomics
Language: English
Subfield: Obstetrics and Gynecology
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
Funders: American Heart Association, National Institutes of Health, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, National Heart, Lung, and Blood Institute, National Center for Advancing Translational Sciences, National Institute on Minority Health and Health Disparities, Eunice Kennedy Shriver National Institute of Child Health and Human Development
Awards: Texas Center for Minority Health, Education, Research and Outreach, Vasopressin and Preeclampsia: Early Mechanisms for Prevention, Mechanisms of Early and Late Postpartum Hypertension in Human Preeclampsia, University of Iowa Strategically Focused Hypertension Research Center, Molecular Mechanisms of Vasopressin-Induced Preeclampsia, G7805842754, The University of Iowa Clinical and Translational Science Award, Maternal vascular responses to extracellular mitochondrial DNA during pregnancy, G864428963, University of Iowa Hawkeye Intellectual and Developmental Disabilities Research Center (Hawk-IDDRC)
OpenAlex ID: W4376613482