Health System Related Barriers to Multidrug-resistant Tuberculosis (mdr-tb) Care in an Indian Setting: From Patients’ Perspective
Year: 2023
Type: article
Abstract: S1-S35were unmasking TB.Symptoms predictive of IRIS appeared to be refractory pyrexia more than 10 days after VL treatment initiation and enlarged abdominal necrotic lymph nodes on enrolment ultrasound.Incidence of IRIS reduced with increasing the gap between ATT and ART initiation from two to three weeks for those who were ART naïve, and improved early diagnosis.Case fatality rate of TB-VL-HIV patients was 17.9%(n = 5), compared to 1.6% (n = 2) in VL-HIV patients (p < 0.01).Conclusion: VL-HIV patients should all be screened for TB using CBNAAT.The results suggest that VL treatment results in substantial IRIS that may require delayed initiation of ART, while severe IRIS-associated TB remains a major risk in this cohort of patients.
Authors: J. Jagtap, S. Atre, Y. Dumbare, M. Faqih, T. Sawant, S. Ambike, J.S. Bhawalkar, M. Farhat
Language: English
Subfield: Infectious Diseases
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $2,500
OpenAlex ID: W4377042675