Work

Immunogenicity Outcomes of a Randomized, Multicenter, Interventional, First-in-human, Phase 1/2a Study of Vac52416 (expec10v), a Vaccine Candidate for the Prevention of Invasive Escherichia Coli Disease

Year: 2023

Type: article

Abstract: stantiated events were greatest in the WHO African Region (1684 events, 31%) and the WHO Region of the Americas (1312 events, 24%) and, similarly, by year, the burden was highest in those WHO regions.Globally, over time, two-thirds (3536, 65%) of substantiated events were initially reported by WHO and infectious diseases (4298, 79%) were the predominant cause of public health events.However, other causes, including animal origin or zoonoses were also important and disaster related events were on the rise in recent years, particularly in some WHO Regions.Conclusion: WHO has a robust system for global disease detection but health threats are continuously evolving.The impact of climate change and zoonoses is becoming more pronounced, emphasizing the importance of a One Health approach for disease detection.

Source: International Journal of Infectious Diseases

DOI: 10.1016/j.ijid.2023.04.282